Antiinflammatory 3H-naphtho[1,2-d]imidazoles

Details Antiinflammatory 3H-naphtho[1,2-d]imidazoles Antiinflammatory 3H-naphtho[1,2-d]imidazoles

1982-06-24

1984-03-06

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

548326, 564428, A61K 31415, C07D23518

Patent

active

044354177

ABSTRACT:
3H-naphtho[1,2-d]imidazole derivatives of formula ##STR1## wherein R stands for (C.sub.1-6)alkyl, (C.sub.3-6)alkenyl, (C.sub.3-6)alkynyl or (C.sub.3-7)cycloalkyl, R.sub.1 and R.sub.2, each independently may represent hydrogen, halogen, (C.sub.1-4)alkyl, (C.sub.1-4)alkylthio, (C.sub.1-4)alkoxy or halo(C.sub.1-4)alkoxy, R.sub.3 stands for hydrogen, hydroxy, methoxy, ethoxy, or mono- or di-methylamino, and R.sub.4 represents hydrogen or (C.sub.1-4)alkyl.
Also described and claimed are their use as antiinflammatory agents and the pharmaceutical compositions containing them.

REFERENCES:
patent: 4340607 (1982-07-01), Toja et al.
Yoshida, Z., et al., Chemical Abstracts, 48: 11398c (1954) [J. Chem. Soc., Japan, Ind. Chem. Sect. 55, 354-356 (1952)].
Omodei-Sale, A., et al., Chemical Abstracts, 85: 192731p (1976) [German OLS 2,551,868, 8/12/76].

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