Certain substituted .beta.-oxo-.alpha.-carbamoylpyrrolepropionit

Details Certain substituted .beta.-oxo-.alpha.-carbamoylpyrrolepropionit Certain substituted .beta.-oxo-.alpha.-carbamoylpyrrolepropionit

1982-01-07

1984-03-06

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546281, 546143, 546159, 548195, 548222, 548251, 544238, 544324, 544405, C07D40112, A61K 3144

Patent

active

044354070

ABSTRACT:
.beta.-Oxo-.alpha.-(heterocyclic substituted carbamoyl)-.beta.-pyrrolyl-propionitriles are antiinflammatory and/or antiarthritic agents with immunomodulating properties. Their synthesis, pharmaceutical compositions thereof, and methods of treatment utilizing such compounds are included.

REFERENCES:
patent: 4061767 (1977-12-01), Ertel et al.
patent: 4256759 (1981-03-01), Walker
J. Am. Chem. Society 35 959 (1913).
Chem. Abstracts 74, 12358g (1971).

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