N-[2-(Pyridinyl)-4-pyrimidinyl]ureas preparation

Details N-[2-(Pyridinyl)-4-pyrimidinyl]ureas preparation N-[2-(Pyridinyl)-4-pyrimidinyl]ureas preparation

1976-07-12

1977-10-11

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424251, C07D40104, A61K 3117, A61K 3144

Patent

active

040534758

ABSTRACT:
N--R.sub.3 --N--R.sub.4 --N'--(2--Q--5--R.sub.1 --6--R.sub.2 --4-Pyrimidinyl)ureas which are useful as anti-allergic agents are prepared by reacting a 2--Q--4--RNH--5--R.sub.1 --6--R.sub.2 -pyrimidine with an R.sub.4 '-isocyanate and reacting the intermediate product with 1,1'-carbonyldiimidasole.

REFERENCES:
brown, Heterocyclic Compounds; The Pyrimidines, Supp. I, 1970, Interscience, N.Y., pp. 259-261.

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