Method for introducing amino groups into benzimidazole or imidaz

Details Method for introducing amino groups into benzimidazole or imidaz Method for introducing amino groups into benzimidazole or imidaz

1976-02-23

1977-06-21

Randolph, John D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

71 92, 424263, 424273, 2602948C, 2603092, C07D23514, C07D47104

Patent

active

040311074

ABSTRACT:
The present invention is a process for the introduction of a nucleophilic group into a benzimidazole or imidazo[4,5-b or c]pyridine ring, which comprises treating a derivative of the corresponding 1-hydroxybenzimidazole or -imidazo[4,5-b or c]pyridine with a nucleophilic reagent. The process can also be used to reduce the 1-hydroxybenzimidazole or -imidazo[4,5-b or c]pyridine.

REFERENCES:
patent: 3875173 (1975-04-01), Doherty
patent: 3932428 (1976-01-01), Doherty
Takahashi et al., I, Chem. Pharm. Bull., vol. 12, pp. 282-291, (1964).
Takahashi et al., II, Chem. Pharm. Bull., vol. 14, pp. 375-385, (1966).
Chemical Abstracts, vol. 76, abst. no. 53629j (1972), (abst. of German Offen. 2,022,504).

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