Method of inhibiting the influx of leukocytes into organs during

Details Method of inhibiting the influx of leukocytes into organs during Method of inhibiting the influx of leukocytes into organs during

1989-03-31

1992-09-15

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Lymphokine

53038822, 5303887, 43524027, A61K 3900, A61K 3514, C12N 500

Patent

active

051476371

ABSTRACT:
The influx of leukocytes into the lung and other organs during sepsis or other infectious or non-infectious trauma can be inhibited by the administration of anti-CD18 monoclonal antibodies. Such inhibition results in a prevention and/or diminishment of organ damage in inflammations and especially in endotoxic shock and adult respiratory distress syndrome.

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