Sialic acid derivatives

Details Sialic acid derivatives Sialic acid derivatives

1992-03-04

1995-08-01

Robinson, Douglas W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 5, 536 61, 536 182, 536 187, 536 53, 536 551, 536123, 530395, C07H 1500, C07H 1524, C08B 3700

Patent

active

054381258

ABSTRACT:
Sialic acid compounds of formula ##STR1## wherein X is hydrogen, a lower alkyl group or benzyl, Y is hydrogen or acetyl, Ac is acetyl, and the wavy line represents that the compound of the formula (I) includes both a .alpha.-anomer and .beta.-anomer, have excellent chemical and enzymatical stability and are useful in the treatment of central or peripheral nervous diseases.

REFERENCES:
patent: 4797477 (1989-01-01), Yoshimura et al.
patent: 4990603 (1991-02-01), Ogawa et al.
patent: 5023239 (1991-06-01), Ogura et al.
patent: 5034516 (1991-07-01), Roy et al.
patent: 5037969 (1991-08-01), Minami et al.
patent: 5057605 (1991-10-01), Yoshimura et al.
patent: 5077397 (1991-12-01), Yoshimura et al.
Laine et al; J. Biol. Chem. 249(14): 4460-4466 (1974).
Parikh et al; Methd. Enzymol. 34: 610-619 (1974).
Ponpipom et al; Can. J. Chem. 58:214-220 (1980).
Lindahl et al, Chemical Abstracts 107: 26512k (1987).
Levery et al; Carb. Res. 178: 121-144 (1988).
DeVries et al; Arch. Biochem. Biophys. 151: 243-250 (1972).
Okamoto et al; Tet. Lett. 27(43): 5229-5232 (1986).
Okamoto et al; Tet. Lett. 27(43): 5233-5236 (1986).
Okamoto et al; Bull. Chem. Soc. Jpn. 60: 637-643 (1987).
Okamoto et al; Tetrahedron 43(24): 5919-5928 (1987).
Okamoto et al; Tetrahedron 44(4): 1291-1298 (1988).
Paulsen et al; Liebigs, Ann. Chem. 3: 277-279 (1988).
Lee et al; Biol. Chem. Hoppe Seyler 371: 307-316 (Apr. 1990).

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