N-substituted aminomethanediphosphonic acids

Organic compounds -- part of the class 532-570 series – Organic compounds – Phosphorus acids or salts thereof

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558158, C07F 938, A61K 3166

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active

052817482

ABSTRACT:
N-substituted aminomethanediphosphonic acids of the formula I, ##STR1## wherein R.sub.1, X, alk.sub.1, R.sub.2 and n are as defined in the description, and salts thereof, have valuable pharmaceutical properties and are effective e.g. in the treatment of conditions which can be associated with disorders of the calcium metabolism. They are manufactured in a manner known per se.

REFERENCES:
patent: 3919297 (1975-11-01), Krueger et al.
patent: 4761406 (1988-08-01), Flora et al.
patent: 4927814 (1990-05-01), Gall et al.
patent: 4942157 (1990-07-01), Gall et al.
patent: 5036058 (1991-07-01), Jaeggi
Minne et al., The Hypercalcaemic Syndrome in Rats Bearing the Walker Carcinosarcoma 256. Acta Endocrinologica, 78, pp. 613-624 (1975).
Kaibara et al., Pathogenetic Difference between Collagen Arthritis and Adjuvant Arthritis. J. Exp. Med. 159, pp. 1388-1396 (1984).
Newbould, Chemotherapy of Arthritis induced in Rats by Mycobacterial Adjuvant, Brit. J. Pharmacol., 21, pp. 127-136 (1963).
Patent Abstr. Japan, vol. 3, No. 63 (C-47) May 30, 1979 of JP 54-37829 (1979).
Chem Abst 89, 221805f (1978).
Chem Abst 85, 33126d (1976).
Derwent Abst. 83-766213 of EP 88359 (1983).
Derwent Abstr. 46125w (1975).
Derwent Abstr. 17167x (1976).
Derwent Abstr. 87-079621 (1987).
Derwent Abstr. 88-029414 (1988).

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