Process for the preparation of 17.alpha.-bromoethynyl- and 17.al

Details Process for the preparation of 17.alpha.-bromoethynyl- and 17.al Process for the preparation of 17.alpha.-bromoethynyl- and 17.al

1983-11-16

1985-10-29

Roberts, Elbert L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514182, C07J 100, A61K 3156

Patent

active

045501009

ABSTRACT:
A process for preparing bromine- or iodine-unlabeled or radioactively labeled 17.alpha.-bromoethynyl- and 17.alpha.-iodoethynyl-17.beta.-hydroxy steroids of the androstane and estrane series of the partial formula ##STR1## wherein is a single bond or a double bond,

REFERENCES:
patent: 3121079 (1964-02-01), Oberster et al.
patent: 3959322 (1976-05-01), Hughes et al.
Burgess et al., Tetrahedron 23; (1967), pp. 4111-4116.
Mazaitis, The Journal of Nuclear Medicine (1980) 21; pp. 142-146.
Salomon et al., Helv. Chim. Acta 30:1616 (1947).

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