Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Hydrolases
Patent
1998-08-24
2000-03-21
Naff, David M.
Drug, bio-affecting and body treating compositions
Enzyme or coenzyme containing
Hydrolases
424 941, 424 9461, 424 9463, 424 9464, 424 9467, 424601, 514912, 52612313, A61K 3843, A61K 3846
Patent
active
060399430
ABSTRACT:
A thimerosal-free hyaluronidase is prepared wherein the preferred hyaluronidase is devoid of molecular weight fractions below 40,000 MW, between 60-70,000 MW and above 100,000 MW. Also a method for accelerating the clearance of hemorrhagic blood from the vitreous humor of the eye is carried out by contacting at least one hemorrhage-clearing enzyme (e.g., hyaluronidase, .beta.-glucuronidase, matrix metalloproteinase, chondroitinase, chondroitin sulfatase or protein kinase) with the vitreous humor in an amount which is effective to cause accelerated clearance of blood therefrom.
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Riets
Aragon Gabriel Arturo Carpio
Gutierrez Flores Jose Luis
Karageozian Hampar L.
Karageozian Vicken H.
Kenney Maria Cristina
Advanced Corneal Systems
Kerr Janet M.
Naff David M.
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