Process for resolution of racemates of 4-aryl-2-oxo-pyrrolidine-

Details Process for resolution of racemates of 4-aryl-2-oxo-pyrrolidine- Process for resolution of racemates of 4-aryl-2-oxo-pyrrolidine-

1993-02-18

1996-07-23

Bernhardt, Emily

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544372, 546208, 548531, 548551, 435117, 435118, 435121, 435122, 435280, C07D20712, C12P 1710, C12P 1712, C12P 1716

Patent

active

055391117

ABSTRACT:
An enzymatic process employing pancreatin or choelsterol esterase for resolution of racemates of 4-aryl-2-oxo-pyrrolidine-3-carboxylic acid esters of general formula I ##STR1## in which X represents a carbon-carbon bond or an oxygen atom,

REFERENCES:
patent: 4012495 (1977-03-01), Schmiechen et al.
patent: 4588694 (1986-05-01), Hamaguchi et al.
patent: 4732853 (1988-03-01), Whitesides et al.
patent: 4879421 (1989-11-01), Kazlauskas
patent: 5180671 (1993-01-01), Nishizawa et al.
patent: 5286650 (1994-02-01), B anziger et al.
Sakimae et al, Chemical Abstracts, vol. 112, No. 97019 (1990) (Abstract for JP 63/198998, Aug. 17, 1988).
Francalanci et al, Chemical Abstracts, vol. 108, No. 166108 (1988) (Abstract for EP 237983, Sep. 23, 1987).
Iriuchijima et al, Chemical Abstracts, vol. 97, No. 106411 (1982).
Iriuchijima et al, Agric. Biol. Chem. 46, p. 1593 (1982).
Marivet et al, J. Med. Chem., 32, p. 1450 (1989).
Gu et al, Tetrahedron Letters 27 pp. 5203-5206 (1986).

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