Treatment of cancer with imidazo-1,2-pyridazin compounds

Details Treatment of cancer with imidazo-1,2-pyridazin compounds Treatment of cancer with imidazo-1,2-pyridazin compounds

1995-06-02

1996-07-23

Criares, Theodore J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

A61K 31495

Patent

active

055389708

ABSTRACT:
Compounds of general formula (I) ##STR1## wherein R.sup.1 represents an optionally substituted carbocyclic or heterocyclic aryl group, or an optionally substituted alkyl, alkenyl, cycloalkyl or cycloalkenyl group; R.sup.2 represents an optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl or cycloalkenyl group or an optionally substituted carbocyclic or heterocyclic aryl or aralkyl group; R.sup.3 represents a hydrogen atom or an alkyl group; and either X represents an oxygen or sulphur atom, a group, --CH.sub.2 -- or a group NR.sup.4 where R.sup.4 represents a hydrogen atom or a C.sub.1-4 alkyl group; and Y represents a group --CH.sub.2 -- or --CH.sub.2 CH.sub.2 -- or X--Y together represent the group --CH.dbd.CH--; and salts and physiologically functional derivatives thereof are useful in the treatment of tumors. Processes for preparing the compounds, intermediates useful in their preparation, pharmaceutical compositions containing them and their use in the treatment of tumors are also described.

REFERENCES:
Chemotherapy of Cancer; Carter et al, (1981); A. Wiley Medical Publication, pp. 361-365.

Affiliated with

Also associated with

Rating

Treatment of cancer with imidazo-1,2-pyridazin compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Treatment of cancer with imidazo-1,2-pyridazin compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Treatment of cancer with imidazo-1,2-pyridazin compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-713218