Salts of tetracyclines

Details Salts of tetracyclines Salts of tetracyclines

1994-06-24

1996-07-23

Peselev, Elli

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 111, 536 41, 53612313, 536121, 536122, 552203, A61K 3170, C07H 500

Patent

active

055389546

ABSTRACT:
A salt of sucrose-octa-O-sulfonic acid and a tetracycline useful in inhibiting protein synthesis of bacteria.

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S. Saivin et al.; "Clinical Pharmacokinetics of Doxycyline and Minocycline"; Clinical Pharmacokinetics; 15:355-366 (1988).
M. Schach von Wittenau; "A Symposium on Doxycycline: Pharmacokinetics of Doxycycline"; OPMSAZ; 33:5-10 (1974).
M. J. Story et al.; "Doxycycline Tolerance Study: Incidence of Nausea after doxycycline administration to healthy volunteers: A comparison of 2 formulations (Doryx'vs vibramycin')"; Eur. J. Clin. Pharmacol; 40:419-421 (1991).
Desmond B. Williams et al.; "Absorption of Doxycycline from a Controlled Release Pellet Formulation: The Influence of Food on Bioavailability"; Biopharmaceutics & Drug Disposition; vol. 11; pp. 93-105 (1990).

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