Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1985-03-18
1988-08-02
Lee, Mary C.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
546297, 546300, 546307, 546310, 546311, 546335, 424 3, 436800, C07D21368, C07D21365, C07D21373, C07D21355
Patent
active
047614811
ABSTRACT:
It is disclosed that aryl-substituted 2,6-bis[N,N-di(carboxyalkyl)aminoalkyl] pyridines in which the aryl groups are substituted with one or more electron-releasing groups are an advantageous ligand for forming fluorescent chelates with rare earth metals. The pyridine moieties can be linked to target molecules, especially biologically active target molecules to provide fluorescent tagging for use in fluoroassay techniques. The pyridine moieties are disclosed as tetraacids, as salts and as esters. Preparation processes and precursors including the corresponding aryl-substituted 2,6-dicarboxypyridines as acids, salts and esters, are disclosed as well.
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Hale Ron L.
Solas Dennis W.
Baxter Travenol Laboratories Inc.
Bjorkman Dale A.
Fentress S. B.
Flattery P. C.
Hartenberger R. E.
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