Process for the purification of the blood clotting factors, II,

Details Process for the purification of the blood clotting factors, II, Process for the purification of the blood clotting factors, II,

1982-01-19

1983-10-25

Cintins, Ivars C.

Liquid purification or separation

Processes

Ion exchange or selective sorption

210691, 210927, 260112B, B01D 1500

Patent

active

044117949

ABSTRACT:
A process for purifying liquids containing blood clotting factors by adsorption of the factors on mineral adsorbents such as calcium phosphate, aluminum hydroxide gel, barium sulfate or hydroxylapatite in the presence of calcium ions followed by elution is described.

REFERENCES:
patent: 4081431 (1978-03-01), Stephan et al.
Hoag et al., "Treatment of Hemophilia B with a New Clotting-Factor Concentrate", New England Journal of Medicine, 280, pp. 581-586, Mar. 13, 1969.

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