Indwelling catheter with stable enzyme coating

Details Indwelling catheter with stable enzyme coating Indwelling catheter with stable enzyme coating

1995-04-25

1996-07-23

Yasko, John D.

Surgery

Means for introducing or removing material from body for...

Treating material introduced into or removed from body...

424423, A61M 532, A61F 200

Patent

active

055385117

ABSTRACT:
An improved indwelling catheter adapted for long-term usage includes a stable enzyme coating to prevent occlusion of the catheter lumen. The enzyme coating includes a fibrinolytic and/or lipolytic enzyme incorporated in a catheter coating to resist or control proteolytic degradation, thereby maintaining the enzyme in an active state for dissolving clots and occlusions within the catheter lumen over an extended period of time.

REFERENCES:
patent: 4879135 (1989-11-01), Greco et al.
patent: 5001062 (1991-03-01), Larsson et al.
patent: 5019393 (1991-05-01), Ito et al.
patent: 5061237 (1991-10-01), Gessler et al.
patent: 5244799 (1993-09-01), Anderson
patent: 5298255 (1994-03-01), Sawamoto et al.

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