Epimerization of malonic acid esters

Organic compounds -- part of the class 532-570 series – Organic compounds – Chalcogen in the nitrogen containing substituent

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C07D49804

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active

045046581

ABSTRACT:
A compound represented by the formula (II) epimerizes by the action of a base and the product is precipitated for shifting the equilibrium to yield the corresponding epimer represented by the formula (I). ##STR1## wherein Ar is an optionally substituted aryl or heterocyclic group;

REFERENCES:
patent: 3719667 (1973-03-01), Gutowski
patent: 4138486 (1979-02-01), Narisada et al.
patent: 4167630 (1979-09-01), Firestone
patent: 4234596 (1980-11-01), Christensen et al.
patent: 4320055 (1982-03-01), Blaszczak
patent: 4323567 (1982-04-01), Narisada et al.

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