Benzhydrylpiperazine derivatives, process for their preparation

Details Benzhydrylpiperazine derivatives, process for their preparation Benzhydrylpiperazine derivatives, process for their preparation

1983-12-27

1985-03-12

Coughlan, Jr., Paul M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544396, A61K 31495, C07D29502

Patent

active

045044813

ABSTRACT:
The invention relates to new benzhydrylpiperazine derivatives of the formula (I) ##STR1## wherein n is 2 or 3, and acid addition salts thereof. According to another aspect of the invention there are provided processes for the preparation of these compounds.
The compounds of the formula (I) are pharmacologically active. More particularly, they inhibit the microsomal monooxigenase enzyme system of liver. Pharmaceutical compositions containing them as active ingredient are also within the scope of the invention.

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