Extended human hematopoiesis in a heterologous host

Details Extended human hematopoiesis in a heterologous host Extended human hematopoiesis in a heterologous host

1995-05-04

1997-04-29

Chambers, Jasemine C.

Multicellular living organisms and unmodified parts thereof and

Nonhuman animal

800DIG2, 800DIG5, 424553, 424580, 424582, 424577, 424578, 424 92, 424 937, 424579, 623 11, A61K 3500

Patent

active

056251270

ABSTRACT:
A human hematopoietic system is provided in an immunocompromised mammalian host, where the hematopoietic system is functional for extended periods of time. Particularly, human fetal liver tissue and human fetal thymus is introduced into an appropriate site of a young immunocompromised mouse at a site supplied with a vascular system, whereby the fetal tissue results in novel formation of functional human bone marrow tissue.

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