Synthesis of thymosin .alpha..sub.1 and desacetyl thymosin .alph

Details Synthesis of thymosin .alpha..sub.1 and desacetyl thymosin .alph Synthesis of thymosin .alpha..sub.1 and desacetyl thymosin .alph

1983-04-04

1985-03-12

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07C10352

Patent

active

045044155

ABSTRACT:
An improved solution phase synthesis of thymosin .alpha..sub.1 and desacetyl thymosin .alpha..sub.1 with t-Boc side chain protection and proceeding through novel intermediates is disclosed.

REFERENCES:
patent: 4079127 (1978-03-01), Goldstein et al.
patent: 4116951 (1978-09-01), Wang
patent: 4148788 (1979-04-01), Wang
patent: 4353821 (1982-10-01), Birr et al.
Birr et al., Angew. Chem. Int. Ed. Engl., 18(5), 394-395, (1979).
Abiko et al., Chem. Pharm. Bull., 30(5), 1776-1783, (1982).
Wang et al., J. Am. Chem. Soc., 101(1), 253-254, (1979).

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