Stereoselective process for making endo-tropanamine and like com

Details Stereoselective process for making endo-tropanamine and like com Stereoselective process for making endo-tropanamine and like com

1995-04-28

1997-04-29

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546126, C07D45102, C07D45106

Patent

active

056250657

ABSTRACT:
A stereoselective process for forming compounds related to 4-endotropanamine through the reactive amination of a corresponding ketone with a triacyloxy borohydride.

REFERENCES:
patent: 4921982 (1990-05-01), Cohen et al.
Robertson, et al., J. Med. Chem., 35, 310-319 (1992).
Abdel-Magid and Maryanoff, Syn. Lett., 537-539 (1990).
Abdel-Magid, et al., Tet. Lett., 31 (39), 5595-5598 (1990).
Hutchins, et al., J. Org. Chem., 48, 3412-3422 (1983).
Gribble and Nutaitis, Org. Prep. Proced. Int., 17 (4-5), 317-384 (1985).

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