Protein kinase C inhibitors

Details Protein kinase C inhibitors Protein kinase C inhibitors

1995-03-30

1997-04-29

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

540456, 540450, A61K 3155, A61K 31395

Patent

active

056249497

ABSTRACT:
This invention provides novel bis-indolemaleimide macrocycle derivatives of the formula: ##STR1## The invention further provides the preparation, pharmaceutical formulations and the methods of use for inhibiting Protein Kinase C in mammals.

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