Trans platinum (IV) complexes

Details Trans platinum (IV) complexes Trans platinum (IV) complexes

1994-09-13

1997-04-29

Berch, Mark L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514185, 514186, 514187, 544225, 546 10, 548101, 548108, 548109, 548402, C07F 1500, A61K 31555

Patent

active

056249195

ABSTRACT:
Novel trans-platinum IV complexes which contain heterocycle ligands such as quinoline or isoquinoline, anionic ligands such as halide or sulfate, and which optionally may contain ammonia, or a primary or secondary amine are provided. These complexes have application as pharmaceuticals, in particular as anti-tumor agents.

REFERENCES:
Massacesi, G.T. Inorg Biochem. 29, 95(1987).
Hazarika, Polyhedron 3, 121-124 (1984).
Singhal, T. Indian Chem Soc 18A, p. 449 (1979).
Kukushkin, Zh. Neorg. Khim. 26(8), 2190 (1981).
Floris, Trans. Met. Chem 17, 145-146(1992).

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