Method reducing TNF-alpha in mammals with cerebral malaria

Details Method reducing TNF-alpha in mammals with cerebral malaria Method reducing TNF-alpha in mammals with cerebral malaria

1994-08-30

1997-04-29

Kunz, Gary L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514895, 536 2623, 536 2626, 536 2763, A61K 3170, C07H 19167, C07H 1920

Patent

active

056249136

ABSTRACT:
A method for reducing the TNF-alpha in mammals with cerebral malaria comprising the administration of 2-methylthio-ATP or 2-chloro-ATP.

REFERENCES:
patent: 3678162 (1972-07-01), Maguire et al.
patent: 3752805 (1973-08-01), Maguire et al.
patent: 3860706 (1975-01-01), Ikeda et al.
patent: 4826823 (1989-05-01), Cook et al.
patent: 4918061 (1990-04-01), Raetz et al.
patent: 5106837 (1992-04-01), Carson et al.
patent: 5310732 (1994-05-01), Carson et al.
Tanke, et al. Abstract summarizing a poster presentation at the 1989 ASCB meeting, p. 17.
Tanke, et al. Abstract, 30th ICAAC meeting, Atlanta, Georgia, Oct. 1990, p. XIX.
Tanke, et al. article titled "Lipid X inhibition of bacterial lipopolysaccharide-stimulated GTP-ase activity", Cellular and Molecular Aspects of endotoxin reactions, A. Nowotny et al., Editors, pp. 227-237 (1990).
Lehninger, Albert. Biochemistry: The Molecular Basis of Cell Structure and Function; Second Edition, Worth Publishers, Inc. (New York), p. 730.
Sigma Chemical Catalog, 1992, pp. 676-677.
Gough, et al. article, "Three New Adenosine Triphosphate Analogs: Synthesis and Effects on Isolated Gut", Journal of Medicinal Chemistry, 1973, vol. 16, No. 10, pp. 1188-1190.
Proctor, et al. article, "Protection of mice from endotoxic death by 2-methylthio-ATP", Proc. Natl. Acad. Sci. USA, vol. 91, pp. 601-6020, Jun. 1994 Microbiology.

Affiliated with

Also associated with

Rating

Method reducing TNF-alpha in mammals with cerebral malaria does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method reducing TNF-alpha in mammals with cerebral malaria, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method reducing TNF-alpha in mammals with cerebral malaria will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-705723