Process for the preparation of pure flupirtine maleate and its A

Details Process for the preparation of pure flupirtine maleate and its A Process for the preparation of pure flupirtine maleate and its A

1998-04-23

1999-09-28

Davis, Zinna Northington

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D21375

Patent

active

059591153

ABSTRACT:
A process for preparation of pure flupertine maleate and the pure A crystalline form of flupertine maleate by the use of water soluble alcohols during synthesis and/or purification.

REFERENCES:
patent: 4481205 (1984-11-01), von Bebenburg et al.
S. Schwoch et al., 2,3-Dihydrospiro'1H-4-an 5-azabenzimidazole-2, 1'-cyclohexane|: Reactions with nucleophiles, Helvetica Chimica Acta, vol. 77, 1994, pp. 2175-2190.

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