Intermediate imidazole acrolein analogs

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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548110, 548343, C07D23364

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active

046687947

ABSTRACT:
Compounds of the formula ##STR1## and the pharmaceutically acceptable acid addition salts thereof, wherein the various substituents are defined hereinbelow, the use thereof for inhibiting cholesterol biosynthesis and lowering the blood cholesterol level and, therefore, in the treatment of hyperlipoproteinemia and atherosclerosis, pharmaceutical compositions comprising such compounds and processes for and intermediates in the synthesis of such compounds.

REFERENCES:
patent: 3983140 (1976-09-01), Endo et al.
patent: 4198425 (1980-04-01), Mitsui et al.
patent: 4248889 (1981-02-01), Oka et al.
patent: 4255444 (1981-03-01), Oka et al.
patent: 4308378 (1981-12-01), Stokker
patent: 4351844 (1982-09-01), Patchett et al.
patent: 4361515 (1982-11-01), Terahara et al.
patent: 4375475 (1983-03-01), Willard et al.
patent: 4376863 (1983-03-01), Lam
patent: 4387242 (1983-06-01), Lam
patent: 4440927 (1984-04-01), Prugh
patent: 4474971 (1984-10-01), Wareing
patent: 4503072 (1985-03-01), Hoffman et al.
patent: 4530922 (1985-07-01), Moberg
F. Hulcher, Arch. Biochem. Biophys., 146, 422-427 (1971).
A. Sato, et al., Chem. Pharm. Bull., 28, 1509-1525 (1980).
F. Singer, et al., Proc. Soc. Exp. Biol. Med., 102, 370-373 (1959).

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