Nucleic acid multimers and amplified nucleic acid hybridization

Details Nucleic acid multimers and amplified nucleic acid hybridization Nucleic acid multimers and amplified nucleic acid hybridization

1995-06-07

1997-04-29

Marschel, Ardin H.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 71, 435810, 436501, 536 221, 536 231, 536 241, 536 243, 536 2431, 536 2432, 536 2433, 935 77, 935 78, C12Q 168, C07H 2104

Patent

active

056248024

ABSTRACT:
Linear or branched oligonucleotide multimers useful as amplifiers in biochemical assays which comprise (1) at least one first single-stranded oligonucleotide unit that is complementary to a single-stranded oligonucleotide sequence of interest, and (2) a multiplicity of second single-stranded oligonucleotide units that are complementary to a single-stranded labeled oligonucleotide. Amplified sandwich nucleic acid hybridizations and immunoassays using the multimers are exemplified.

REFERENCES:
patent: 4299916 (1981-11-01), Litman et al.
patent: 4428941 (1984-01-01), Galibert et al.
patent: 4563419 (1986-01-01), Ranki et al.
patent: 4749647 (1988-06-01), Thomas et al.
patent: 4828979 (1989-05-01), Klevan et al.
patent: 4882269 (1989-11-01), Schneider et al.
patent: 4894325 (1990-01-01), Englehardt et al.
patent: 4910300 (1990-03-01), Urdea et al.
patent: 5124246 (1992-06-01), Urdea et al.
Chu et al., "Synthesis of an amplifiable reporter RNA for bioassays" Nucleic Acids Research (1986) 14(14):5591-5603.
Syvanen et al., "Fast quantification of nucleic acid hybrids by affinity-based hybrid collection" Nucleic Acids Research (1986) 14(12):5037-5048.
Syvanen et al., "Quantification of polymerase chain reaction products by affinity-based hybrid collection" Nucleic Acids Research (1988) 16(23):11327-11338.
Damha et al. (1989) Tetrahedron Letters, vol. 30, No. 46, pp. 6295-6298.
Kierzek et al. (1986) Nucleic Acids Research, vol. 14, No. 12, pp. 4751-4764.

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