Thiazolylacetamido cephalosporin compounds

Details Thiazolylacetamido cephalosporin compounds Thiazolylacetamido cephalosporin compounds

1986-01-23

1987-05-26

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540228, C07D50120, A61K 31545

Patent

active

046687831

ABSTRACT:
Novel cephem compounds of the formula: ##STR1## wherein R.sup.4 is a residue of a nucleophilic compound selected from hydroxyl, mercapto, cyano, azido, amino, carbamoyloxy, carbamoylthio and thiocarbamoyloxy, said group being unsubstituted or substituted by alkyl of up to three carbons, and R.sup.5 is hydroxyl or lower alkoxy, or a pharmaceutically acceptable ester thereof, have strong antibiotic properties against a wide variety of microorganisms.

REFERENCES:
patent: 4380541 (1981-04-01), Ochiai et al.
patent: 4520194 (1985-05-01), Ochiai et al.

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