Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-06-07
1997-09-09
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
424 49, 424 54, A61K 722, A61K 3147, A61K 31485
Patent
active
056657315
ABSTRACT:
A process is provided which is useful in alleviating inflammation of gums, bone loss and detachment of teeth in a patient in need of such treatment. The process comprises administering a vasodilator to the inflamed gum tissue and other affected tissue, either topically or by injection. Advantageously, the vasodilator is papaverine or a pharmaceutically acceptable salt thereof such as papaverine hydrochloride. Advantageously, the papaverine hydrochloride may be administered topically in a composition comprising a carrier such as an aqua based transparent gel dental vehicle. The carrier dissolves the papaverine hydrochloride and enables it to penetrate the soft tissue of the gums and be absorbed into the inflamed tissue.
REFERENCES:
patent: 2507086 (1950-05-01), Baizer
patent: 3823234 (1974-07-01), Mauvernay
patent: 3832460 (1974-08-01), Kosti
patent: 3910921 (1975-10-01), Esanu
patent: 4018927 (1977-04-01), Voorhees
patent: 4055648 (1977-10-01), Sache
patent: 4089943 (1978-05-01), Roberts et al.
patent: 4136173 (1979-01-01), Pramoda et al.
patent: 4440777 (1984-04-01), Zupan
patent: 4529584 (1985-07-01), Mulvey et al.
patent: 4529585 (1985-07-01), Hayes
patent: 4758433 (1988-07-01), Johnson et al.
patent: 4801587 (1989-01-01), Voss et al.
patent: 5059603 (1991-10-01), Rubin
patent: 5278172 (1994-01-01), Hennessey
patent: 5487897 (1996-01-01), Polson et al.
Batterman et al., CA74(1):2610a (Chemical Abstracts) 1970.
Matveikov et al., 89:185149 Biosis, BA87:96415, 1988.
Rusin et al., "Papaverine and Ro 20-1724 Inhibit Cyclic Nucleotide Phosphodiesterase Activity and Increase Cyclic AMP Levels in Psoriatic Epidermis in Vitro", J. Invest. Derm., 71: 154-156 (1978).
Batterman et al., Angiology 21(9), pp. 612-626, 1970.
"Advances in Dentistry", John Hopkins Medical Letter, 4-6 (Jul. 1993).
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