Amides and esters of 2-[N-(morpholinoalkyl)aminosulfonyl]-6-nitr

Details Amides and esters of 2-[N-(morpholinoalkyl)aminosulfonyl]-6-nitr Amides and esters of 2-[N-(morpholinoalkyl)aminosulfonyl]-6-nitr

1985-11-06

1986-07-29

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544159, A61K 31535, C07D29514

Patent

active

046031332

ABSTRACT:
Amide and ester derivatives of 2-[N-(morpholinoalkyl)aminosulfonyl]-6-nitrobenzoic acids are disclosed to have activity in increasing the sensitivity of hypoxic tumor cells to therapeutic radiation. Also disclosed are methods of preparing such compounds and pharmaceutical compositions including such compounds.

REFERENCES:
patent: 4396622 (1983-08-01), Jozic

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