Chimeric glycoproteins containing immunogenic segments of human

Details Chimeric glycoproteins containing immunogenic segments of human Chimeric glycoproteins containing immunogenic segments of human

1992-09-04

1994-02-08

Baker, Keith

Chemistry: molecular biology and microbiology

Spore forming or isolating process

4352542, 4353201, 435 697, 4351723, C12N 1585, C12N 516, C12N 500

Patent

active

052847640

ABSTRACT:
This invention encompasses novel chimeric glycoproteins which are useful for preparing virus specific immune responses against human parainfluenza virus type 3, PIV3. Host cells transformed with structural genes coding for the glycoproteins, expression and replication plasmids containing the structural genes, vaccines made from the glycoproteins and methods for protecting humans by inoculation with said vaccines are also part of this invention.

REFERENCES:
patent: 4743553 (1988-05-01), Rice
Spriggs (1988) J. Virol. 62, 1293-1296.
Ray et al (1988) J. Virol. 62, 783-787.
Ray et al. (1985) J. Infect. Dis. 152, 1219-1230.
Campo in "DNA Cloning Vol. II" (D. M. Gloren Ed.) IRL Press, Wash. DC pp. 213-238 (1986).
Luckow et al. (1988) Bio/Technology 6, 47-55.
Coleingh et al (1987) Virology 160, 465-472.
Elango et al (1986) J. Virol. 57, 481-489.
Spriggs et al. (1986) Virology 152, 241-251.
Thomsen et al (1984) Proc. Natl. Acad. Sci. 81, 659-663.

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