Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Enzymatic production of a protein or polypeptide
Patent
1984-03-05
1986-11-04
Marantz, Sidney
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Enzymatic production of a protein or polypeptide
4351722, 435240, 435241, 435284, 435948, 530399, 935106, 935109, C12P 2100, C12N 1500, C12N 500, C12N 502
Patent
active
046210504
ABSTRACT:
A process for the mass production of hCSF, comprises cell fusion of human lymphoblastoid cells with any human cells capable of producing said substance, in vivo multiplication of the resultant hybridoma cells, using a non-human warm-blooded animal, and in vivo cultivation of the multiplied hybridoma cells to produce hCSF. The hCSF production according to the present process is much higher than that attained by conventional processes; thus, hCSF can be used in a sufficient amount in the prevention and treatment of human diseases.
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DeSantis Patricia L.
Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
Marantz Sidney
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