Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1995-06-05
1998-11-03
Fox, David T.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
4351723, 4353201, 435325, 536 235, C07H 2104, C12N 1585, C12N 1512
Patent
active
058310665
ABSTRACT:
The present invention provides novel anticode oligomers and methods of using them for controlling the growth of cancer cells expressing the bcl-2 gene.
REFERENCES:
patent: 4999290 (1991-03-01), Lee
patent: 5015568 (1991-05-01), Tsujimoto et al.
patent: 5098890 (1992-03-01), Gewirtz
patent: 5149628 (1992-09-01), Croce
patent: 5202429 (1993-04-01), Tsujimoto et al.
patent: 5585479 (1996-12-01), Hoke et al.
Orkin SH, et al. "Report and Recommendations of the Panel to Assess the NIH Investment in Research on Gene Therapy.", Dec. 7, 1995.
Toshiyuki Miyashita et al, Cancer Research, vol. No. 52, pp. Nos. 5407-5411, Oct. 1, 1992.
Toshiyuki Miyashita et al, Blood, vol. No. 81, pp. Nos. 151-157, Jan. 1, 1993.
J. C. Reed et al, Annals of Oncology, 1993, pp. Nos. 61-65.
F. E. Cotter et al, Oncogene, vol. No. 9, pp. Nos. 3049-3055, Oct. 1994.
Shinichi Kitada et al, Antisense Research and Development, vol. No. 4, pp. Nos. 71-79, Summer 1994.
Shinichi Kitada et al, Antisense Research and Development, vol. No. 3, pp. Nos. 157-169, Summer 1993.
Reed et al, Cancer Res., 50, p. No. 5656, 1990.
Williams, Cell 65, p. No. 1097, 1991.
Strasser et al, Cell 67, p. No. 889, 1991.
Patent Cooperation Treaty (PCT) International Search Report dated Jan. 12, 1995.
C. Paoletti, "Anti-Sense Oligonucleotides as Potential Antitumour Agents: Prospective Views and Preliminary Results," Anti-Cancer Drug Design, vol. 2, p. Nos. 325-331, 1988.
Stein et al, "Oligodeoxynucleotides as Inhibitors of Gene Expression: A Review," Cancer Research, vol. 48, p. Nos. 2659-2668, May 15, 1988.
Eugen Uhlmann et al."Antisense Oligonucleotides: A New Therapeutic Principle," Chemical Reviews, vol. 90, No. 4, p. Nos. 544-584, Jun. 1990.
Tsujimoto, Y., et al, Proc. Natl. Acad. Sci. USA, vol. 83, p. Nos. 5214-5218, Jul. 1986.
Negrini, M., et al, Cell, vol. 49, p. Nos. 455-463, 1987.
Reed, J., et al, Science, vol. 236, p. Nos. 1295-1299, Jun. 5, 1987.
Fox David T.
Nelson Amy J.
The Trustees of the University of Pennsylvania
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