Directed evolution of thermophilic enzymes

Details Directed evolution of thermophilic enzymes Directed evolution of thermophilic enzymes

1996-12-05

1998-11-03

Achutamurthy, Ponnathapura

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

530350, C12P 2106, C07K 100

Patent

active

058306960

ABSTRACT:
Thermostable enzyme are subjected to mutagenesis to produce a thermophilic enzyme which is stable at thermophilic temperature and which has increased activities at least two-fold higher than the activity of the wild-type thermostable enzyme at lower temperatures, which are temperatures of 50.degree. C. or lower.

REFERENCES:
patent: 5352778 (1994-10-01), Comb et al.
patent: 5500363 (1996-03-01), Comb et al.

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