Taxoids, their preparation and pharmaceutical compositions conta

Details Taxoids, their preparation and pharmaceutical compositions conta Taxoids, their preparation and pharmaceutical compositions conta

1995-06-07

1998-09-29

Richter, Johann

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549510, 549511, 548215, A61K 31335, C07D30514

Patent

active

058146580

ABSTRACT:
New taxoids of general formula (I), their preparation, and pharmaceutical compounds containing them. ##STR1## In general formula (I), for example, Ar represents an aryl radical,

REFERENCES:
patent: 5254580 (1993-10-01), Chen et al.
patent: 5294637 (1994-03-01), Chen et al.
patent: 5532388 (1996-07-01), Bouchard et al.
Gueritte-Voegelein et al., "Relationships between the Structure of Taxol Analogues and Their Antimitotic Activity," J. Med. Chem. 1991, 34, 992-998.
Klein et al., "Synthesis of Ring B-Rearranged Taxane Analogs," J. Org. Chem. 1994, 59, 2370-2373.

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