Pyridylalkyl imidazole-2-thiols

Details Pyridylalkyl imidazole-2-thiols Pyridylalkyl imidazole-2-thiols

1985-08-02

1987-01-06

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546278, 546294, 546295, A61K 31415, C07D40106

Patent

active

046347119

ABSTRACT:
Potent dopamine-.beta.-hydroxylase inhibitors having the formula: ##STR1## which are useful to inhibit dopamine-.beta.-hydroxylase activity, pharmaceutical compositions including these inhibitors, and methods of using these inhibitors to inhibit dopamine-.beta.-hydroxylase activity in mammals. Also disclosed are novel intermediates useful in preparing the presently invented inhibitors.

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