Optically active pyridonecarboxylic acid derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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546156, 544 62, 544128, 544363, C07D47102, C07D21522, C07D40102, C07D41302, C07D41702

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active

060311029

ABSTRACT:
N.sub.1 -(1,2-cis-2-halogenocyclopropyl)-substituted pyridonecarboxylic acid derivatives represented by the following formula (I) the terms of which are defined in the specification and the salts thereof are disclosed: ##STR1## These compounds have patent antibacterial activities against a wide variety of infectious bacteria and are useful as antibacterial agents by oral or parenteral administration.

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patent: 5587386 (1996-12-01), Hayakawa et al.
Synthesis and Antibacterial Activity of N.sub.1 -2-Fluorocyclopropyl-4-Quinolone Derivatives; Research Institute, Daiichi Seiyaku Co., Ltd. 1987, Japan. (Kimura I).
Therapeutics in the 21st Century; The Japanese/U.S.Congress of Pharmaceutical Sciences; Dec. 4-7, 1987; Hawaii (Kimura II).

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