Methods for the treatment of gastrointestinal tract disorders

Drug – bio-affecting and body treating compositions – Lymphokine

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

424 852, 514 12, 514 21, A61K 3818, A61K 3819, A61K 3820, A61K 3830

Patent

active

058143084

ABSTRACT:
Methods for treating gastrointestinal tract disorders by protection, regeneration and repair of intestinal epithelium are described. Macrophage stimulating protein is found to promote colony formation by crypt cells and may be involved in stimulating proliferation of intestinal crypt cells. Also described are pharmaceutical compositions for MSP and methods for identifying substances that stimulate crypt cell proliferation.

REFERENCES:
patent: 5219991 (1993-06-01), Leonard et al.
patent: 5234908 (1993-08-01), Szabo et al.
patent: 5315000 (1994-05-01), Degen
Gaudino et al., Oncogene 11, 2627-2637 (1995) (Abstract only).
Thomas et al., GUT 35, 1742-1746 (1994) (Abstract only).
Burgess et al., J. of Gastroentenol-Hepatol. 5, 10-21 (1990).
Carson, Histotechnology: A Self-Instructional Text American Society of Clinical Pathologist Press pp. 158-160 (1990).
Degen et al., Biochemistry 30, 9781-9791 (1991).
Falk et al. Am. J. Physiol. 266, G987-1003 (1994).
Fausset and Lu Electrophoresis 12, 22-27 (1991).
Gaudino et al. EMBO J. 13, 3524-3532 (1994).
Gordon et al., FASEB 6, 3039 (1992).
Harlow and Lane Antibodies: A Laboratory Manual, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY (1988). (Table of Contents Only).
Housely et al., J. Clin. Invest. 94, 1764-1777 (1994).
Johnson et al., J. Cell Biol., 118, 741 (1992).
Kuniyashi et al., Jpn. J. Cancer Res. 82, 969 (1991).
Leonard et al. Exp. Cell Res. 114, 117 (1978).
Leonard et al. Exp. Cell. Res. 102, 434 (1976).
Malden et al. Int. J. Cancer 43, 380 (1989).
Merewether et al. in Techniques in Protein Chemistry VI, pp. 153-160 (1995).
Podolsky, Am. J. Physiol. 246, G179 (1993).
Remington's Pharmaceutical Sciences, 18th ed. Gennaro, ed. Mack, Easton, PA (1990) (Table of Contents Only).
Ronsin et al. Oncogene 8, 1196-1202 (1993).
Wang et al. Science 266, 117-119 (1994).
Whitehead et al. In Vitro Cellular & Developmental Biology, 23, 436-442 (1987).
Whitehead, Cancer Res. 47, 2683 (1987).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Methods for the treatment of gastrointestinal tract disorders does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods for the treatment of gastrointestinal tract disorders, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for the treatment of gastrointestinal tract disorders will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-684024

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.