Diagnostic applications of mouse ascites golgi (MAG) manipulatio

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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128738, 435806, 436 65, 436814, 436906, G01N 3353, A61B 1000

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active

055996809

ABSTRACT:
Therapeutic and diagnostic applications by the detection and manipulation of mouse ascites golgi factor produced by endometrium and present in other exocrine tissues and defined by an antibody found in mouse ascites are provided by this invention.

REFERENCES:
Arceci et al., "The Gene Encoding Multidrug Resistance is Induced and Expressed at High Levels During Pregnancy in the Secretory Epithelium of the Uterus", Proc. Natl. Acad. Sci. USA 85: 4350-4354 (1988).
Axiotis et al., "P-Glycoprotein Expression is Increased in Human Secretory and Gestational Endometrium", Laboratory Investigation 65: 577-581 (1991).
Axiotis et al., "Rapid Communication: Immunohistochemical Detection of P-Glycoprotein in Endometrial Adenocarcinoma", Amer. J. of Pathology 138: 799-806 (1991).
Finstad et al., "Some Monoclonal Antibody Reagents (C219 and JSB-1) to P-Glycoprotein Contain Antibodies to Blood Group A Carbohydrate Determinants: A Problem of Quality control for Immunohistochemical Analysis", J. Histochemistry and Cytochemistry 39: 1603-1610 (1991).
Smith et al., "Endogenous and monoclonal Antibodies to the Rat Pancreatic Acinar Cell golgi Complex," J. Cell Biol 98: 2035-2046 (1984).
Thiebaut et al., "Cellular Localization of the Multidrug-Resistance Gene Product P-Glycoprotein in Normal Human Tissues", Proc. Natl. Acad. Sci. USA 84: 7735-7738 (1987).
Kliman et al, 1995. A Mucin-Like Glycoprotein Identified by MAG (Mouse Ascites Golgi) Antibodies. Menstrual Cycle-Dependent Localization in Human Endometrium Am J Pathol 146:166-181.

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