Reagent for measuring direct bilirubin

Details Reagent for measuring direct bilirubin Reagent for measuring direct bilirubin

1994-12-28

1997-02-04

Kight, John

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

435 25, 435 28, 436 63, 436 97, 436 74, C12Q 100, C12Q 126, G01N 3348, G01N 3320

Patent

active

055996612

ABSTRACT:
A reagent system and method are described for optically measuring direct bilirubin by the reaction of a bilirubin oxidase, oxidizing agent or diazonium salt, with the direct bilirubin, wherein a tetrapyrrole compound is provided in the presence of the bilirubin oxidase, oxidizing agent or diazonium salt. It is possible to accurately measure the direct bilirubin, which is known to increase considerably in the biological fluids of patients having obstructive jaundice, etc. The reagent system and method are useful in clinical settings, etc.

REFERENCES:
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patent: 4788153 (1988-11-01), Detwiler et al.
patent: 4892833 (1990-01-01), Weiss et al.
patent: 5112769 (1992-05-01), Modrovich
patent: 5149272 (1992-09-01), Wu et al.
patent: 5262304 (1993-11-01), Taniguchi
patent: 5278073 (1994-01-01), Grandjean

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