Dibenzoxazepine N-carboxylic acid hydrazines and derivatives

Details Dibenzoxazepine N-carboxylic acid hydrazines and derivatives Dibenzoxazepine N-carboxylic acid hydrazines and derivatives

1975-08-25

1976-11-16

Milestone, Norma S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260240R, C07D26720

Patent

active

039923754

ABSTRACT:
Derivatives of the dibenzoxazepine N-carboxylic acid hydrazides are acylated to yield N,N'-diacyl hydrazines which are useful pharmacological agents as is evidenced by their anti-arrhythmic, anti-inflammatory, anti-diarrheal, prostaglandin antagonist and 5-hydroxytryptamine antagonist activity.

REFERENCES:
patent: 3534019 (1970-10-01), Coyne et al.
patent: 3624104 (1971-11-01), Cusic
William E. Coyne et al., Jour. Med. Chem., 11 (6), (1968), pp. 1158-1160.

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