Process for the production of N-formyl-alpha-L-aspartyl-L-phenyl

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters

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C07C10102

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active

048208612

ABSTRACT:
N-formyl-.alpha.-L-aspartyl-L-phenylalanine methyl ester is obtained by reacting L-phenylalanine methyl ester with N-formyl-L-aspartic acid anhydride in a reaction solvent containing acetic acid or acetic acid and formic acid in a complete mixing type continuous reaction mode.

REFERENCES:
patent: 3833553 (1974-09-01), Ariyoshi et al.
patent: 3901871 (1975-08-01), Anderson
patent: 3933781 (1976-01-01), Bachman et al.
patent: 4071511 (1978-01-01), Takemoto et al.
patent: 4656304 (1987-04-01), Oppici et al.

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