Method for purifying tryptophan

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D20920

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active

048208256

ABSTRACT:
A process for purifying tryptophan produced by microbial cells or an enzyme is disclosed. In this process, the microbial cells are separated, the solution containing tryptophan is treated at a pH in the range of 1 to 4 with activated carbon and a non-polar highly porous resin and crystallized under neutralization in the presence of a lower aliphatic alcohol or a lower aliphatic ketone.
The thus purified tryptophan has a transmission of 95% and more.

REFERENCES:
patent: 2416956 (1947-03-01), Sahyun
patent: 3450712 (1969-06-01), Samejima
patent: 3801457 (1974-04-01), Arima et al.

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