Process for the continuous production of acrylamide or methacryl

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing nitrogen-containing organic compound

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435174, 435177, 435182, 435832, 435822, 435840, 435843, 435859, 435872, C12P 1302, C12N 1100, C12N 1102, C12N 1104, C12R 101, C12R 107, C12R 113, C12R 115, C12R 1265, C12R 1365

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044408587

ABSTRACT:
A process for the continuous production of acrylamide or methacrylamide from acrylonitrile or methacrylonitrile by use of a microorganism capable of promoting the hydration of acrylonitrile or methacrylonitrile into the corresponding amide.
Said process comprising immobilizing the microorganism or enzyme extracted therefrom, continuously bringing the acrylonitrile or methacrylonitrile into contact with the immobilized microorganism or enzyme in at least one reactor containing an aqueous medium at a pH pf 6 to 10 to cause the hydration reaction, and recycling a part of the reacted solution to dilute the unreacted acrylonitrile or methacrylonitrile and water therewith.

REFERENCES:
patent: 4001081 (1977-01-01), Commeyras et al.
patent: 4248968 (1981-02-01), Watanabe et al.
Vieth et al., Applied Biochemistry and Bioengineering, vol. 1, Academic Press, New York, 228-229 (1976).
Brodelius, Advances in Biochemical Engineering, vol. 10, Springer-Verlag, New York, 75, 84, 85 (1978).

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