2-Acetyl quinoline thiosemicarbazones useful in treatment of gon

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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42424851, 424250, 424257, 2602444, 544128, 544363, 546 15, 546104, 546168, 546175, C07D21512, A61K 3147

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active

044407718

ABSTRACT:
This invention relates to the preparation and use of various 2-acetyl quiine thiosemicarbazones which are substituted on the 4-nitrogen atom. These compounds are useful in the treatment of gonorrhea and, in addition, many are useful either in the treatment of malaria or bacterial infections, such as leprosy and meningitis.

REFERENCES:
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Jorgenson, Organic Reactions, vol. 18, pp. 1-97, (1970).
Fujikawa, et al., Chemical Abstracts, vol. 68, 29557b, (1968).
Hogarth, et al., Chemical Abstracts, vol. 44, 4143a, (1950).
Knotz, Chemical Abstracts, vol. 67, 43724q, (1967).
Borsche, et al., Chemical Abstracts, vol. 31, 4069, (1937).

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