Monoclonal antibody capable of specifically distinguishing human

Details Monoclonal antibody capable of specifically distinguishing human Monoclonal antibody capable of specifically distinguishing human

1985-06-27

1989-04-11

Moskowitz, Margaret

Chemistry: molecular biology and microbiology

Spore forming or isolating process

530387, 424 11, 424 853, 435 68, 435 70, 4351722, 935104, 935107, 935110, C12N 500, C12N 1200, C07K 1504

Patent

active

048206415

ABSTRACT:
The specification discloses a monoclonal antibody capable of distinguishing human hepato-carcinoma cells, a hybridoma producing said monoclonal antibody and a process for preparing the monoclonal antibody using said hybridoma. The monoclonal antibody of the invention specifically attackes hepato-carcinoma cells in vivo.

REFERENCES:
patent: 4579827 (1986-04-01), Sakamoto
Seto, M. et al., Cancer Research, 43: 4768-4773 (10-1983).
Seto, M. et al., Cancer Reserach, 46: 2056-2061 (4-1986).
Shouval, D. et al., Proc. Natl. Acad. Sci., U.S.A. 79(2): 650-654, (1982) cited in Biosis Abstract 82: 223133.
Sasanami, T., Sapporo Igaku Zasshi, 53(3): 223-241, (1984), cited in Chemical Abstract CA101(7): 53030v.
Miller et al.; Blood, vol. 58, No. 1 (Jul.) 1981; pp. 78-86; In Vivo Effects of Murine Hybridoma Monoclonal Antibody . . . Leukemia.
Hepatology, vol. 2, No. 5, 1982, p. 677; Antibodies to a Human Hepatoma Cell Line . . . Patterns.
Ritz et al.; Blood, vol. 58, No. 1 (Jul.) 1981; pp. 141-152; Serotherapy of Acute Lymphoblastic Leukemia with Monoclonal Antibody.

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