Method and therapeutic system for treating aqueous deficient dry

Details Method and therapeutic system for treating aqueous deficient dry Method and therapeutic system for treating aqueous deficient dry

1975-10-28

1976-11-16

Medbery, Aldrich F.

Surgery

Respiratory method or device

Ozone or ion generation

128249, A61M 700, A61M 3100

Patent

active

039917592

ABSTRACT:
Method for treating aqueous deficient dry eye by instilling a biologically compatible solute, such as sodium chloride, into the tear film continuously at a controlled rate that is sufficient to osmotically induce a continuous flow of water from the interstitial fluid to the tear film and thereby correct the aqueous deficiency. The method may be carried out by placing a therapeutic system, in the form of an ocular insert, into the cul-de-sac, the insert comprising the solute confined within a polymer matrix that releases the solute continuously at 3 to 20 micromoles of solute species per hour.

REFERENCES:
patent: 3664340 (1972-05-01), Morgan
patent: 3811444 (1974-05-01), Heller
patent: 3818909 (1974-06-01), Braton
patent: 3828777 (1974-08-01), Ness
patent: 3832458 (1974-08-01), Merrill
patent: 3896819 (1975-07-01), Zaffaroni
patent: 3917119 (1975-11-01), Kahn
New Concepts In Ocular Xerosis, Dohlman C. H., Trans. Opthal. Society, UK 91, 105-117 (1971).
Tear Substitutes in the Treatment of Dry Eyes, Lemp, M. A. Int. Opthal. Clin. 13, 145-153 (1973).

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