Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1985-04-04
1989-10-03
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514400, A61K 31415
Patent
active
048717592
ABSTRACT:
A method of treatment for mesenteric adenitis in humans is provided. The method comprises the administration of antiviral agents comprising pharmaceutical derivatives of imidazole. Specifically, mesenteric adenitis is treated with orally administered dosages of metronidazole or cimetidene. When the treatment is with metronidazole, a preferred dosage for average sized adult humans is approximately 1,000 to 2,000 milligrams administered once a day. When the antiviral agent administered is cimetidine, the preferred dosage is 900 to 1,200 milligrams given two times a day. When either cimetidine or metronidazole are given, concurrent treatment with zinc is suggested as a method of speeding recovery.
REFERENCES:
Hollingshed Peritoneal Cavity and Mesenteries, Textbook of Anatomy, 2nd Ed, pp. 115-116, 1967.
Ursing et al., Metronidazole for Chron's Disease, The Lancet, pp. 775-777, Apr. 5, 1975.
Paul Urtrasun, M.D. et al., Radiation and High Dose Metronidazole in Supratentoreal Glioblastomas, New England Journal of Medicine, vol. 294, No. 25, pp. 1364-1367, Jun. 17, 1976.
Kenneth G. Warren, M.D. et al., Isolation of Latent Herpes Simplex Virus From the Superior Cervical and Vagus Ganglions of Human Beings, New England Journal of Medicine, vol. 298, No. 19, pp. 1068-1069, May 11, 1978.
Van Der Spey, et al, Cimetidiene in the Treatment of Herpesverus Infections, S. A. Mediesi Tydskrif, pp. 112-116 Jul. 19, 1980.
Bernstein, et al, Healing of Perineal Chron's Disease with Metronidazole, Gastrosenterology, 79:357-365, 1980.
Brandt et al, Metronidazole Therapy for Perineal Chron's Disease; A Follow-Up Study, Gastroenterology, 83:383-387, 1982.
Hayne and Mercer; Herpes Zoster: Treatment with Cimetidine, The Canadian Medical Assoc. Journal, vol. 129, Dec. 15, 1983.
Geigler, et al, Interaction Between Cimetidine and Metronidazole, Journal of Medicine, vol. 309, No. 24, pp. 1518-1519, Dec. 15, 1983.
Maulight et al., Cimetidine for Herpes Zoster, Journal of Medicine, vol. 310, No. 5, pp. 318-319, Feb. 2, 1984.
News Front, Zinc: Speeding Recovery From the Common Cold, Modern Medicine, Jul., 1984.
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