Immobilization of biologically active protein on a polymeric fib

Chemistry: molecular biology and microbiology – Carrier-bound or immobilized enzyme or microbial cell;... – Enzyme or microbial cell is immobilized on or in an organic...

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435176, 435177, 436524, 436531, 530811, 530815, C12N 1108, C12N 1114, G01N 33545, C07K 1708

Patent

active

047570148

ABSTRACT:
A composite article is prepared comprising in sequence a fibrous polymeric support which has been subjected to a surface treatment to provide binding sites thereon, a layer of a protein immobilizer compound, and a biologically active protein. The surface treatment comprises coating the support with a 2 to 500 nm thick layer of inorganic oxide or subjecting the support to a plasma treatment. The protein immobilizer can be a polymer or silane-functional compound. The biologically active protein can be the enzyme, catalase, which has use in decomposing hydrogen peroxide when disinfecting contact lenses.

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