Method for preventing tissue damage associated with graft-versus

Details Method for preventing tissue damage associated with graft-versus Method for preventing tissue damage associated with graft-versus

1998-09-10

2000-08-01

Krass, Frederick

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514170, 514171, 514177, 514178, 514179, 514180, 514181, 514182, 428451, 428464, 428489, 428490, A61K 3158, A61K 3156, A01N 4500

Patent

active

060967315

ABSTRACT:
A method for preventing tissue damage associated with graft-versus-host disease in a patient having undergone hematopoietic cell transplantation, and host-versus-graft disease in a patient having undergone organ allograft transplantation. The method includes orally administering to the patient a prophylactically effective amount of a topically active corticosteroid, such as beclomethasone dipropionate, for a period of time following hematopoietic cell or organ allograft transplantation, and prior to the presentation of symptoms associated with graft-versus-host disease or host-versus-graft disease. Representative tissues includes tissue of the intestine and liver, while representative tissue damage includes inflammation thereof.

REFERENCES:
patent: 5403833 (1995-04-01), Calne
"Oral Beclomethasone Diproprionate for Treatment of Human Intestinal Graft-Versus Host Disease", Baehr et al, Transplantation 60:1231-1238, Apr. 1995.
"Graft-Versus-Host Effect After Allogenic Hematopoietic Stem Cell Transplantation: GVHD and GVL", Nash et al, Curr. Opin. Immunol., 8(5), 674-680, Mar. 1996.

Affiliated with

Also associated with

Rating

Method for preventing tissue damage associated with graft-versus does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for preventing tissue damage associated with graft-versus, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for preventing tissue damage associated with graft-versus will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-664048