Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1985-06-18
1989-10-03
Teskin, Robin L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 29, 530352, 530806, 436507, 436518, 436523, 436536, 436539, 436541, 436598, C12Q 100, C12Q 102, G01N 33564, G01N 3353
Patent
active
048716618
ABSTRACT:
Materials can be screened for carcinogenic properties by administering them to test animals and assaying biological tissue, preferably plasma, for the presence of a 60K cancer-associated phosphoprotein. The test is applicable to a wide range of chemically-diverse carcinogens and is not restricted to carcinogens having one particular mode of action.
REFERENCES:
patent: 4003789 (1977-01-01), Green
patent: 4066510 (1978-01-01), Thilly
patent: 4256832 (1981-03-01), Findl et al.
patent: 4345026 (1982-08-01), Lew
patent: 4407942 (1983-10-01), Birnboin
patent: 4594319 (1986-01-01), Sharma
Hanausek et al., Cancer Invest vol. 2 (6) pp. 433-441 1984 "Characterization of a 60,000-Dalton Oncofetal Protein from the Plasma of Tumor-Bearing Rats."
Hanausek-Walaszek Margaret
Lang Raymond W.
Schumm Dorothy E.
Walaszek Zbigniew
Webb Thomas E.
Millard Sidney W.
Teskin Robin L.
The Ohio State University Research Foundation
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